Table 1.
Natural products and other small molecules tested against EBOV. (NA = no activity).
Molecule | Name: Function | EC50 Activity (μM; ±SD; n=4) |
HeLa CC50 (μM; n=2) |
AlogP | MWT |
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Nicotinamide: Active Form of Vitamin B3 | NA | NA | −0.32 | 122.13 |
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Nicotinic acid: Vitamin B3 | NA | NA | 0.31 | 123.11 |
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L- menthol: Scent | NA | NA | 2.78 | 156.27 |
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Eugenol: Used in Perfumeries, Flavorings, Essential Oils and in Medicine as a Local | 1.3 ± 0.5 | > 50 | 2.58 | 164.20 |
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P-anisaldehyde: Flavoring ingredient | 2.9 ± 0.6 | > 50 | 1.57 | 136.15 |
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Benzyl acetate: Perfumery and Flavorings | 10.7 ± 5.0 | > 50 | 1.60 | 150.17 |
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Phenethyl acetate: Perfumery and Flavorings | 10.4 ± 3.4 | > 50 | 1.93 | 164.20 |