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Pharmacokinetic properties of compound 9 and 11. Pharmokinetics were studied in male C57BL/6 mice after (a) single intravenous administration of 2 mg/kg Compound 9; (b) single intravenous administration of 2 mg/kg Compound 11; (c) single oral administration of 10 mg/kg Compound 11; (d) single intravenous administration of 10 mg/kg Compound 11. Plasma levels of the compounds were determined by LC-MS/MS analysis at the indicated time points.
