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. 2019 Feb 15;8:190. [Version 1] doi: 10.12688/f1000research.17964.1

Figure 4. Gross appearance and histology of the lungs of SCID mice injected with A549 human lung adenocarcinoma cells via the tail vein.

Figure 4.

(A) lungs from a mouse that did not receive a cancer cell injection; B-C. lungs from mice injected with cells at 5 (B), and 8 (C). Note the white patches on the lungs, which appeared by week 5 (as for H3122 cells above). (D-F) Haematoxylin and Eosin stain of lungs from mice at 3 (D), 5 (E), and 8 (F) weeks after cell injection using a 10x objective. Squares and arrows indicate areas of high cell density. (G-I) Area shown in insets from images D-F respectively, using a 20x objective. (J-L) Area shown in insets from images (D-F) using a 40x objective. Scale bars: D-I 100 µm; J-L 50 µm.