Fig. 8.

Genes underlying baseline refractive eye development and susceptibility to myopia in mice are localized in human QTLs associated with myopia (part 2). Heatmap depicting genes and odds ratios for the overlaps between 109 human myopia QTLs and genes whose expression correlates with either baseline refractive errors, susceptibility to form deprivation myopia, or both in mice. Colors indicate odds ratios. Bold italic identifies genes found to be associated with refractive error in UK Biobank, CREAM, or both human samples by the gene-based genome-wide association analysis. Red identifies genes exhibiting correlation with both baseline refractive development and susceptibility to myopia in mice