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. 2019 Jul 30;19:750. doi: 10.1186/s12885-019-5955-z

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Transmission electron microscopy of IPC-366 (a, d, e) and SUM 149 (b, c, f) mammospheres. d is magnified in e. Groups of joined cells by tight- junctions (TJ) and belt desmosomes (zonula adherens, ZA). Rough endoplasmic reticulum (RER). Swollen and degenerate mitochondrias (M). Autophagic vacuole (AFV). Membrane-derived vesicle (EV). Original magnification; a, b) X 4,000, c) X 6,000, d) X 30,000, e) X 100,000, f) X 60,000