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. 2019 Jul 30;7:200. doi: 10.1186/s40425-019-0684-z

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Tumor volume weakly correlates with edema among NSCLC and melanoma patients. a Representative baseline MRIs taken from patients treated with pembrolizumab showing similar tumor volumes on T1 post gadolinium 3D MP-RAGE (white arrows) but discordant amounts of edema volume on FLAIR sequences. b The correlation between tumor and edema volume of NSCLC and melanoma BMs is weak. c Pre-treatment edema:tumor volumes are not significantly different in melanoma and NSCLC patients