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. 2019 Jul 30;11:1759091419865788. doi: 10.1177/1759091419865788

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© The Author(s) 2019

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 3. — HHcy-associated impairment in spatial learning and memory. (a and b) Mice on HHcy diet made significantly more errors across block and by day than those on control diet. *p < .05, ****p < .001 versus control, mixed measures ANOVA. (c) HHcy mice also made significantly more errors during the probe trial (first trial of each day) on both testing days *p < .05, **p < .01, Mann–Whitney U test. (d) Average velocity across all trials was significantly reduced in the mice on HHcy diet versus controls. **p < .01, student’s t test. N = 10 for control and 12 for HHcy groups.

HHcy = hyperhomocysteinemia.