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. 2019 Jul 30;11:1759091419865788. doi: 10.1177/1759091419865788

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© The Author(s) 2019

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 5. — Four vascular-associated genes are significantly altered as a function of time on HHcy diet. Custom TaqMan arrays were run to measure gene expression changes in selected cerebrovascular-associated genes. Data are expressed as log2 normalized fold changes versus corresponding control group. (a) Adamts1 is significantly downregulated at 4 weeks on HHcy diet but returns to baseline by 8 weeks. (b to d) Slc2a1, Tjp1, and Nostrin are significantly upregulated by 10 to 12 weeks on HHcy diet. **p < .01, ***p < .005 versus corresponding control group, two-way ANOVA, n = 11–12 per group.