Fig. 2.

Tornado diagram showing results of one-way PSA exploring the affect key input variables have on cost-effectiveness of ETEC and Shigella standalone vaccines, in 79 LMICs from 2025 to 2034. Ranges of variables (listed in Table 2) are displayed at the end of the corresponding bar. Price per dose is varied by $US ranging from a low estimate of $2/dose to a high estimate of $7/dose. ‘Etiological fraction’ is variation in the fraction of overall diarrheal mortality attributed to ETEC and Shigella diarrhea. ‘Mortality change’ is variation in the rates diarrheal mortality projected in years 2025–2034. ‘Induced stunting’ refers to the number of other infectious disease deaths caused by ETEC or Shigella induced stunting. ‘Hospitalized fraction’ is variation in the fraction of children hospitalized (1 in 8 referred to inpatient facility).