Fig. 3.

(A) Delivery performance of Nanopatches™ prior to and post transportation, and validation of the Nanopatch™, PoP4 applicator, and force used in rhesus studies. ¹⁴C labelled HPV type 11 Nanopatches™ were applied to pig ears. ‘Before’ samples with or without Coomassie blue (CB) were applied in Australia. ‘Start of Day’ indicates Nanopatches™ that were cold shipped and tested in the USA prior to administration for Rhesus study #1. ‘End of Day’ indicates evaluation of the Nanopatches™ at the conclusion of Rhesus study #1. ‘Start’ and ‘End’ of the day contained Coomassie blue. ‘Retains’ are the same batch of Nanopatches™ tested at Vaxxas (no shipping). ‘Shipped’ samples were Nanopatches™ sent to the USA under cold conditions and returned to Australia. The ‘Fresh coated’ group were not part of the study and were coated after the study, using an identical formulation to the study batch as an experimental control. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)