Fig. 5.

Rhesus Study #2. (A) Histological sections of delivered vaccine payload into Rhesus skin by Nanopatches™. Top Panel: Pseudo-brightfield images generated from the emittance/absorption spectra of the fluorescent images shown in the bottom panel illustrate fine morphological details of the skin tissue. Black is indicative of the injected FluoSpheres®, and blue demonstrates the cellular nuclei. Bottom Panel: Fluorescent green signal indicates the location of the injected FluoSpheres® and blue represents the cellular nuclei, (B) Depth measurements obtained from four quadriceps applications, three forearm applications, one ear application, and two inguinal applications. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)