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. 2019 Jul 26;12:6033–6043. doi: 10.2147/OTT.S209441

Figure 2.

Figure 2

EGCG and Gef synergized in suppressing tumor growth in the xenograft mouse model. (A) Inhibitory effects of different treatments on tumor volume in a xenograft mouse model. Data are shown as mean ± SEM. *P<0.05 vs Gef-alone treatment group, #P<0.05 vs EGCG-alone treatment group (n=10). (B) Illustration of the survival periods of xenograft-bearing mice treated with different treatments. Control (normal saline), EGCG (200 mg/kg/day, p.o.), Gef (10 mg/kg/day, p.o.), Gef plus EGCG (10 mg/kg/day Gef +200 mg/kg/day EGCG, p.o.). Day 0 was used to represent the starting of treatment (n=10).

Abbreviations: EGCG, epigallocatechin gallate; Gef, gefitinib.