Table 4.

Management of agitation and delirium at the end of life

Drug	Route	Starting Dosage
Lorazepam	p.o. (tablet, liquid), i.v., i.m.	2–3 mg/day divided 2–3 times a day
Diazepam	p.o., p.r., i.v., i.m.	2–10 mg every 3–4 h
Clonazepam	p.o., ODT	0.5 mg 3 times a day
Quetiapine	p.o.	25 mg twice a day
Olanzapine	p.o., ODT, i.m.	5 mg daily
Haloperidol	p.o., i.m.	0.5 mg every 1–4 h, as needed

Abbreviations: i.m., intramuscular; i.v., intravenous; ODT, orally disintegrating tablet; p.o., oral; p.r., per rectum