Table 2.
Comparison of ABCB1 polymorphisms with the characteristics
| Characteristics | ABCB-CC | ABCB-CT | ABCB-TT | P |
|---|---|---|---|---|
| Number of patients | 40 | 45 | 16 | 0.061 |
| Recipient age in years (mean) | 32.22 | 33.82 | 30.06 | 0.128 |
| Donor age in years (mean) | 48 | 50.1 | 48.13 | 0.28 |
| Male: Female | 33:7 | 40:5 | 4:12 | 0.212 |
| Live donors | 60% | 80% | 68.75% | 0.741 |
| Mean creatinine (mg/dL) | 1.36 | 1.35 | 1.4 | 0.311 |
| Tacrolimus dose (mg/day) (mean±SD) | 4.5(±2.16) | 4.23(±2.17) | 3.83(±2.29) | 0.575 |
| Tacrolimus level (ng/mL) (mean±SD) | 6.46(±3.15) | 6.31(±2.15) | 7.27(±3.59) | 0.499 |
| L/D ratio (ng/mL/mg/kg/day) (median: IQR) | 74.45 | 87.75 | 116.71 | 0.26 |
| Induction treatment | 42.5% | 31.11% | 25% | 0.10 |
| Rejections | 9 (22.5%) | 9 (20%) | 4 (25%) | 0.65 |
| CNI toxicity | 3 (7.5%) | 4 (8.95) | 2 (12.5%) | 0.32 |
ABCB1: ATP binding cassette subfamily B member1