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. 2019 Jul 31;9:11108. doi: 10.1038/s41598-019-47455-3

Table 1.

Comparisons of EKG profiles among different sources of EV71 viruses via different routes of inoculation.

Routes & EV71
viral strains
EKG phenotypes Incidence (%) possible causes references
Oral, F6 (infectious clone) PR segment depression 4/7 (57%) acute perimyocarditis 31,32
irregular heart rate 2/7 (29%) supraventricular event (SVE), sinus arrhythmia 33
ST elevation 2/7 (29%) myocardial infarction 34
split of P wave 1/7 (14%) atrial enlargement, dilated cardiomyopathy 35
at least one EKG phenotype 5–7/7 (>70%)
Oral, F23 (clinical isolate) irregular heart rate 2/4 (50%) atrial premature contraction 33
lower or no R amplitude 1/4 (25%)

age-related heart mass loss,

old myocardial infarction

35,36
split of P wave 1/4 (25%) atrial enlargement, dilated cardiomyopathy 35
ST elevation 2/4 (50%) myocardial infarction 34
Decreased P wave 1/4 (25%) atrial rhythm 33
at least one EKG phenotype 4/4 (100%)
i.p., F6 (infectious clone) no abnormality detected 4/5 (80%) healthy
Irregular heart rate 1/5 (20%)
i.p., F23 (clinical isolate) no abnormality detected 4/5 (80%) healthy
Minor arrhythmia 1/5 (20%)