Table 3.

Univariate and multivariate overall survival analysis in 170 patients with invasive vulvar cancer.

Parameter	univariate		multivariate
	3-ys OS	p-value	Comparison	HR	95%-CI	p-value
Serum Creatinine		<0.001		2.6	1.3–5.3	0.006
≤1.20	74.8%
>1.20	32.5%
Serum Creatinine		0.01
FIGO tumor stage		<0.001	I vs. II vs. III vs. IV	1.8	1.40–2.30	<0.001
FIGO I	82.1%
FIGO II	59.9%
FIGO III	50.4%
FIGO IV	52.7%
Age		<0.001	>vs. ≤ 66.5 years	2.9	1.6–5.2	<0.001
≤67.7	82.3%
>67.7	59.9%
Grading		0.64
G1	78.2%
G2/G3	67.5%
Nodal involvement		<0.001
N0	81.7%
N1	51.7%

FIGO International Federation of Gynecologists and Obstetrics, OS disease specific survival, HR hazard ratio, CI confidence interval.

Nodal involvement was not included into the multivariate model, since the nodal status is a crucial part of FIGO stage.