Table 3.

The in vitro effects of E. supra-axillaris extract on COX-1, COX-2 and 5-LOX.

Assay	5-LOX	COX-1	COX-2	SI
	IC50 (µg/mL)
Extract	1.61	4.11	0.065	63.2
Celecoxib	—	17.5	0.046	380.4
Diclofenac	2.11	3.8	0.7	5.42
Indomethacin	—	0.034	0.45	0.075
Zileuton	3.21	—	—	—

SI is COX selectivity index which is defined as IC₅₀ (COX-1)/IC₅₀ (COX-2).