Table 2.
Risk factors of severe complications or fistula recurrence – univariate analysis: preoperative parameters.
| Parameter | Patients with mild or no complications (n=25) Group I |
Patients with severe complications or fistula recurrence (n=17) Group II |
p-Value |
|---|---|---|---|
| Fistula parameters | |||
| Fistula output on the day before surgery, ml/day; median (IQR) | 100 (300–50) | 150 (600–100) | 0.231 |
| Fistula output on the day before surgery, >500 ml/day; n (%) | 2 (8) | 5 (29) | 0.068 |
| Number of fistulas; median (IQR) | 1 (1–2) | 2 (4–1) | 0.029 |
| Number of fistulas >1, n(%) | 8 (32) | 11 (65) | 0.038 |
| Clinical parameters | |||
| Age, years; median (IQR) | 61.0 (67.0–47.0) | 55.0 (59.0–45.0) | 0.204 |
| Time since last operation, days, median (IQR) | 150.0 (332.0–73.0) | 85.5 (123.0–52.5) | 0.091 |
| Time since admission to definitive surgery, days median (IQR) | 23.0 (42.0–8.0) | 60.0 (89.0–34.0) | 0.011 |
| Systolic blood pressure, mmHg, median (IQR) | 120 (130–110) | 125 (130–110) | 0.725 |
| Mean blood pressure <70 mmHg, n (%) | 1 (4) | 1 (6) | 0.781 |
| Laboratory parameters | |||
| WBC >11×109/l, n (%) | 2 (8.0) | 4 (23.5) | 0.058 |
| RBC <3.8×1012/l, n (%) | 13 (52.0) | 10 (58.8) | 0.666 |
| HGB <10 g/dl, n (%) | 8 (32.0) | 7 (41.1) | 0.547 |
| HCT <30%, n (%) | 11 (44.0) | 7 (41.1) | 0.857 |
| PLT ×109/l, median (IQR) | 208 (351.0–208.0) | 348 (441.0–195.0) | 0.343 |
| Fibrinogen mg/dl, median (IQR) | 503 (564.0–395.5) | 558 (672.0–369.0) | 0.386 |
| Sodium <135 mmol/l, n (%) | 6 (24.0) | 7 (41.1) | 0.242 |
| Urea >48 mg/dl, n (%) | 5 (20.0) | 3 (17.6) | 0.850 |
| Creatinine >1.1 mg/dl, n (%) | 5 (20.0) | 1 (5.8) | 0.204 |
| Proteins <6.2 g/dl, n (%) | 7 (28.0) | 5 (29.4) | 0.852 |
| Albumins <3.0 g/dl, n (%) | 7 (28.0) | 9 (52.9) | 0.117 |
| Albumins g/dl, median (IQR) | 3.1 (3.4–2.7) | 2.8 (3.5–2.5) | 0.411 |
| Bilirubin >1.2 mg/dl, n (%) | 1 (4.0) | 1 (5.8) | 0.768 |
| AST > 40 U/l, n (%) | 6 (24.0) | 5 (29.4) | 0.696 |
| ALT >56 U/l, n (%) | 5 (20.0) | 2 (11.7) | 0.479 |
| CRP mg/l, median (IQR) | 7.6 (36.2–3.3) | 46.55 (89–11.4) | 0.014 |
| Scales | |||
| ASA III–IV, n (%) | 8 (32.0) | 9 (52.9) | 0.180 |
| APACHE II, median (IQR) | 8 (10–5) | 6 (7–4) | 0.053 |