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. 2019 Jul 31;9:11081. doi: 10.1038/s41598-019-47591-w

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Stereoview of the cofactor and substrate binding sites of bGalE. (A) NAD⁺ binding site of the UDP complex structure. (B) Superimposition of the complex structures with UDP-Glc (white and green for protein and UDP-Glc) and UDP-GlcNAc (cyan and blue for protein and UDP-GlcNAc). NAD⁺ and hydrogen bonds are shown as yellow sticks and dotted lines, respectively.