Table III.
Symptoms and Treatment
| N=252 | |||||||
|---|---|---|---|---|---|---|---|
|
| |||||||
| Total | PD | YOPD | p | ||||
|
| |||||||
| N | breakdown, % | n | breakdown, % | n | breakdown, % | ||
|
|
|
|
|||||
| Main Symptoms; | |||||||
| Number of Persons Who Said They Had Them | |||||||
| Tremors | 252 | 139 (55.2%) | 228 | 122 (53.5%) | 24 | 17 (70.8%) | 0.132(i) |
| Muscle Stiffness and Contraction | 252 | 196 (77.8%) | 228 | 176 (77.2%) | 24 | 20 (83.3%) | 0.612(i) |
| Posture Maintenance Disability | 252 | 190 (75.4%) | 228 | 172 (75.4%) | 24 | 18 (75.0%) | 1.000(i) |
| Immobility | 252 | 202 (80.2%) | 228 | 183 (80.3%) | 24 | 19 (79.2%) | 1.000(i) |
| Frozen Gait | 252 | 184 (73.0%) | 228 | 160 (70.2%) | 24 | 24 (100.0%) | 0.236(i) |
| Pulsive Walking | 252 | 66 (26.2%) | 228 | 55 (24.1%) | 24 | 11 (45.8%) | 0.028*(i) |
| Difficulty Speaking | 252 | 156 (61.9%) | 228 | 137 (60.1%) | 24 | 19 (79.2%) | 0.079†(i) |
| Difficulty Swallowing | 252 | 117 (46.4%) | 228 | 105 (46.1%) | 24 | 12 (50.0%) | 0.831(i) |
| Salivation | 252 | 146 (57.9%) | 228 | 136 (59.6%) | 24 | 10 (41.7%) | 0.127(i) |
| Constipation | 252 | 171 (67.9%) | 228 | 156 (68.4%) | 24 | 15 (62.5%) | 0.646(i) |
| Difficulty Urinating | 252 | 80 (31.7%) | 228 | 70 (30.7%) | 24 | 10 (41.7%) | 0.356(i) |
| Sweating | 252 | 115 (45.6%) | 228 | 99 (43.4%) | 24 | 16 (66.7%) | 0.033*(i) |
| Lack of Sweat | 252 | 22 (8.7%) | 228 | 20 (8.8%) | 24 | 2 (8.3%) | 1.000(i) |
| Hallucinations | 252 | 83 (32.9%) | 228 | 75 (32.9%) | 24 | 8 (33.3%) | 1.000(i) |
| Mask-Like Expression | 252 | 94 (37.3%) | 228 | 81 (35.5%) | 24 | 13 (54.2%) | 0.080†(i) |
| Depression | 252 | 67 (26.6%) | 228 | 58 (25.4%) | 24 | 9 (37.5%) | 0.227(i) |
| Tiring Easily | 252 | 146 (57.9%) | 228 | 134 (58.8%) | 24 | 12 (50.0%) | 0.515(i) |
| Enhanced Sexual Desire | 252 | 22 (8.7%) | 228 | 20 (8.8%) | 24 | 2 (8.3%) | 1.000(i) |
| Reduced Sexual Desire | 252 | 39 (15.5%) | 228 | 32 (14.0%) | 24 | 7 (29.2%) | 0.071†(i) |
| Cognitive Symptoms | 252 | 59 (23.4%) | 228 | 50 (21.9%) | 24 | 9 (37.5%) | 0.125(i) |
| Motor fluctuation | 252 | 111 (44.0%) | 228 | 96 (42.1%) | 24 | 15 (62.5%) | 0.082†(i) |
|
|
|
|
|||||
| average±SD | average±SD | average±SD | |||||
|
|
|
|
|||||
| Off Time Per Day※ | 129 | 4.4±3.3 | 116 | 4.2±2.9 | 13 | 6.4±5.5 | 0.140(ii) |
| Number of Years Until Off Appeared※ | 134 | 6.8±4.9 | 119 | 6.6±4.4 | 15 | 8.6±7.8 | 0.597(ii) |
| Treatment: | |||||||
| People Who Said Yes | |||||||
| Being Treated with Medicine | 252 | 249 (98.8%) | 228 | 226 (99.1%) | 24 | 23 (95.8%) | 0.260(i) |
| Had Surgery | 252 | 18 (7.1%) | 228 | 17 (7.5%) | 24 | 1 (4.2%) | 1.000(i) |
| Getting Rehabilitation | 243 | 181 (74.5%) | 222 | 169 (76.1%) | 21 | 12 (57.1%) | 0.068†(i) |
| Doing Well on Medicine | 232 | 144 (62.1%) | 210 | 130 (61.9%) | 22 | 14 (63.6%) | 1.000(i) |
| Have Adjusted the Medicine Themselves | 248 | 75 (30.2%) | 225 | 67 (29.8%) | 23 | 8 (34.8%) | 0.637(i) |
(i)
Fisher exact test every side
(ii)
Mann-WhitneyU test
*
p<0.05
**
p<0.01
†
p<0.1
※
Only Those Who Have Them