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. 2019 Jul 24;13:254. doi: 10.3389/fnhum.2019.00254

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Copyright © 2019 Papadelis, Kaye, Shore, Snyder, Grant and Rotenberg.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Anatomically defined region of interest (ROI) and corticospinal tracts (CST). (A) The ROIs pre-central gyrus (PrG and cst) and their corresponding CST for a typically developing (TD) child (aged 18 years, upper panel) and a child with hemiplegic cerebral palsy (HCP) overlaid on their magnetic resonance imagings (MRIs). (B) Error bars (mean ± 95% confidence interval) of diffusion parameters [fractional anisotropy (FA), axial diffusivity (AD), mean diffusivity (MD), and radial diffusivity (RD)] for the CST for both hemispheres of TD children and the less affected (LA) and more affected (MA) hemispheres of children with HCP (**p < 0.001).