Table 4.
Demographics and characteristics of non-obese non-T2D, obese non-T2D, and obese T2D subjects.
| Non-T2D | T2D | P-value | ||
|---|---|---|---|---|
| Non-obese (n) | Obese (n) | Obese T2D (n) | ||
| Age (years) | 39.96 ± 1.36 (70) | 46.44 ± 2.05 (39) | 53.10 ± 1.18 (61) | <0.001 |
| BMI (Kg/m2) | 25.11 ± 0.37 (70) | 33.92 ± 0.47 (39) | 34.18 ± 0.31 (61) | <0.0001 |
| Waist/Hip Ratio | 0.83 ± 0.02 (40) | 0.89 ± 0.02 (27) | 0.98 ± 0.03 (47) | 0.0001 |
| TC (mmol/L) | 5.07 ± 0.11 (68) | 5.18 ± 0.17 (39) | 4.88 ± 0.15 (60) | 0.343 |
| HDL (mmol/L) | 1.39 ± 0.05 (68) | 1.31 ± 0.05 (39) | 1.11 ± 0.04 (59) | 0.0002 |
| LDL (mmol/L) | 3.14 ± 0.10 (68) | 3.33 ± 0.15 (39) | 2.97 ± 0.14 (58) | 0.1836 |
| TGL (mmol/L) | 1.21 ± 0.13 (67) | 1.25 ± 0.10 (39) | 1.73 ± 0.16 (60) | 0.0127 |
| FPG (mmol/L) | 5.22 ± 0.16 (67) | 5.53 ± 0.17 (39) | 8.44 ± 0.39 (61) | <0.0001 |
| HBA1C (DCCT %) | 5.54 ± 0.09 (63) | 5.70 ± 0.10 (39) | 8.12 ± 0.22 (61) | <0.0001 |
| Insulin (U/L) | 9.18 ± 0.78 (54) | 10.23 ± 1.23 (18) | 14.11 ± 1.41 (46) | <0.0001 |
| Leptin (μg/ml) | 5417.90 ± 465.83 (55) | 9124.90 ± 856.74 (28) | 7695.24 ± 625.56 (31) | 0.0001 |
| Adiponectin (μg/ml) | 5285.66 ± 361.29 (62) | 4464.58 ± 434.45 (34) | 3669.38 ± 285.85 (56) | 0.0031 |
| HsCRP (μg/mL) | 1687.09 ± 200.18 (61) | 2764.78 ± 321.95 (31) | 4248.08 ± 387.63 (56) | <0.0001 |
Data are presented as mean ± SEM. P-values were calculated using one-way ANOVA. BMI, body mass index; FPG, fasting plasma glucose; HbA1c, glycated hemoglobin; HDL, high-density lipoprotein; HsCRP, high sensitivity c-reactive protein; LDL, low-density lipoprotein; n, number of subjects; TC, Total cholesterol; TGL, triglycerides.