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. 2019 Mar 28;59(4):1410–1421. doi: 10.1021/acs.jcim.8b00820

Table 6. P-Values of a Pairwise Wilcoxon Signed-Rank Test for AUC Results, Comparing All Three Similarity Methods (GED-Based, FP-Based, and SED-Based)a.

  ULS-UDS
GLL&GDD
  SED FP GED SED FP GED
SED   0.273322 0.0678892   4.26037 × 10–08* 3.34327 × 10–12*
FP 0.273322   0.465209 4.26037 × 10–08*   0.0018207*
GED 0.0678892 0.465209   3.34327 × 10–12* 0.0018207*  
  CAPST
MUV
  SED FP GED SED FP GED
SED   0.0678892 0.0678892   0.000351533* 0.00748178*
FP 0.0678892   0.465209 0.000351533*   0.0615039
GED 0.0678892 0.465209   0.00748178* 0.0615039  
  DUD-E
NRLiSt_BDB
  SED FP GED SED FP GED
SED   0.109745 0.00768579*   0.0520334 3.02696 × 10–05*
FP 0.109745   0.00768579* 0.0520334   0.00167307*
GED 0.00768579* 0.00768579*   3.02696 × 10–05* 0.00167307*  
a

The test is done using all targets separated by datasets. Here, a confidence level of α = 0.05 is used, so p-values lower than α indicate statistically significant differences, which are marked with an asterisk (*) in the table.