Table 1:
Baseline characteristics of the study population, stratified by BMI group
| Characteristic | BMI<30 (N=186) | BMI 30–35 (N=210) | BMI≥35 (N=217) | p† |
|---|---|---|---|---|
| Age (years) | 54.4±9.6 | 53.8±10.8 | 50.5±10.8 | <0.001 |
| Male | 82.3% | 81.0% | 78.3% | 0.597 |
| BMI (kg/m2) | 27.4±2.0 | 32.4±1.4 | 39.9±4.1 | <0.0001 |
| Current Smoker | 24.3% | 20.5% | 22.7% | 0.654 |
| Excessive Alcohol | 3.3% | 3.8% | 3.7% | 0.963 |
| Hypertension | 25.4% | 34.0% | 50.9% | <0.0001 |
| Cardiovascular Disease | 3.2% | 4.8% | 4.6% | 0.769 |
| Diabetes Mellitus | 2.2% | 2.4% | 6.5% | 0.045 |
| Participate in Exercise | 73.6% | 57.6% | 51.9% | <0.0001 |
| Epworth Sleepiness Scale | 11.7±4.8 | 11.4±5.1 | 12.3±5.3 | 0.183 |
| AHI (events/hour) | 37.4±15.2 | 44.7±20.4 | 49.0±23.2 | <0.0001 |
| ODI (events/hour) | 26.4±13.4 | 35.1±18.9 | 41.9±23.5 | <0.0001 |
| SaO2 Nadir | 79.0±6.6 | 76.9±7.5 | 73.2±8.9 | <0.0001 |
| Percent Time SaO2<90 | 6.1±9.1 | 12.4±16.1 | 19.7±22.3 | <0.0001 |
| Total Cholesterol (mg/dL) | 212.6±37.3 | 207.2±42.4 | 200.9±41.5 | 0.016 |
| Total Cholesterol ≥200‡ | 65.6% | 57.6% | 52.5% | 0.029 |
| LDL Cholesterol (mg/dL) | 156.1±35.2 | 152.1±38.2 | 145.4±36.9 | 0.012 |
| LDL Cholesterol ≥130‡ | 76.3% | 71.9% | 65.0% | 0.040 |
| HDL Cholesterol (mg/dL) | 43.6±14.3 | 39.6±9.2 | 38.2±9.4 | <0.0001 |
| HDL Cholesterol <40‡ | 48.4% | 57.1% | 67.3% | 0.001 |
| Triglycerides (mg/dL) | 147.1±63.2 | 177.9±81.6 | 198.9±103.2 | <0.0001 |
| Triglycerides ≥150‡ | 43.0% | 59.5% | 68.7% | <0.0001 |
Significant differences shown in bold.
†
p-values from ANOVA and chi-square or Fisher’s exact test
‡
Based on the NCEP ATPIII published criteria[28]
BMI: body mass index; AHI: apnea-hypopnea index; ODI: oxygen desaturation index; LDL: low-density lipoprotein; HDL: high-density lipoprotein.