Table 3:
Baseline and follow-up characteristics* of the PAP adherent and non-users within the PS designed sample
| Characteristic | Baseline |
Follow-Up |
||||
|---|---|---|---|---|---|---|
| Adherent (N=199) | Non-User (N=118) | p† | Adherent (N=199) | Non-User (N=118) | p‡ | |
| Age (years) | 51.8±10.4 | 52.8±10.0 | 0.996 | – | – | – |
| Male | 81.9% | 80.5% | 0.967 | – | – | – |
| BMI (kg/m2) | 33.9±5.9 | 33.1±5.9 | 0.975 | 34.9±6.1 | 32.9±5.4 | <0.0001 |
| Current Smoker | 20.6% | 20.3% | 0.897 | 18.7% | 28.0% | 0.004 |
| Excessive Alcohol | 2.5% | 2.5% | 0.954 | 1.5% | 2.5% | 0.342 |
| Hypertension | 33.2% | 28.8% | 0.892 | 33.8% | 30.5% | 0.953 |
| Cardiovascular Disease | 2.5% | 1.7% | 0.949 | 2.5% | 1.7% | 0.688 |
| Diabetes Mellitus | 1.5% | 0.9% | 0.987 | 3.1% | 3.5% | 0.460 |
| Participate in Exercise | 58.8% | 58.4% | 0.988 | 67.9% | 66.7% | 0.726 |
| Epworth Sleepiness Scale | 12.0±5.0 | 11.5±4.8 | 0.966 | 7.8±4.6 | 9.3±4.9 | 0.002 |
| AHI (events/hour) | 44.8±19.6 | 40.8±19.8 | 0.931 | – | – | – |
| ODI (events/hour) | 36.1±19.3 | 32.1±19.0 | 0.990 | – | – | – |
| SaO2 Nadir | 76.2±7.5 | 77.5±7.3 | 0.993 | – | – | – |
| Percent Time SaO2<90 | 2.1±1.0 | 1.8±1.0 | 0.942 | – | – | – |
| Total Cholesterol (mg/dL) | 204.7±41.6 | 204.9±35.4 | 0.917 | 211.4±41.6 | 213.3±36.0 | 0.528 |
| Total Cholesterol ≥200§ | 56.3% | 55.1% | 0.727 | 64.3% | 63.6% | 0.771 |
| LDL Cholesterol (mg/dL) | 149.4±37.3 | 149.7±33.8 | 0.933 | 149.5±30.9 | 151.3±33.3 | 0.475 |
| LDL Cholesterol ≥130§ | 70.9% | 72.9% | 0.905 | 75.9% | 72.9% | 0.475 |
| HDL Cholesterol (mg/dL) | 40.0±12.4 | 39.8±10.3 | 0.922 | 46.6±12.8 | 47.3±12.8 | 0.619 |
| HDL Cholesterol <40§ | 60.8% | 57.6% | 0.978 | 30.6% | 34.8% | 0.144 |
| Triglycerides (mg/dL) | 174.8±86.1 | 176.0±102.9 | 0.998 | 174.6±88.9 | 167.9±96.1 | 0.517 |
| Triglycerides ≥150§ | 59.8% | 55.1% | 0.737 | 54.8% | 49.2% | 0.544 |
Significant differences shown in bold
*
Summary statistics presented as mean and standard deviations or percentages of the overall sample, not accounting for PS subclass
†
p-value adjusted for PS subclass from ANCOVA model or conditional logistic regression
‡
p-value from ANCOVA or conditional logistic examining the difference in follow-up values, adjusted for PS subclass and baseline value
§
based on the NCEP ATPIII published criteria[28].
PAP: positive airway pressure; BMI: body mass index; AHI: apnea-hypopnea index; ODI: oxygen desaturation index; LDL: low-density lipoprotein; HDL: high-density lipoprotein