Table 1. Characteristics of Ext1^+/-Ext2^+/- and control mice.

	NSD		HSD
	Control	Ext	Control	Ext
Plasma	(n = 11)	(n = 11)	(n = 5)	(n = 5)
Na+ (mM)	150.8±2.1	149.9±1.5	155.6±0.5†	153.0±1.2†
K+ (mM)	5.4±0.3	5.4±0.5	4.4±0.5†	5.1±0.4
HCO3- (mM)	17.4±3.8	18.0±2.7	18.3±1.8†	20.8±1.6
Glucose (mM)	9.0±1.6	9.1±1.9	7.5±1.6	7.3±0.5
Urea (mM)	7.9±0.8	8.6±0.5	6.0±0.4†	6.0±1.0†
Osmolality (mOsm/kg)	320±5	326±6*	323±5†	323±5
Intake	(n = 16)	(n = 13)	(n = 6)	(n = 11)
Water (ml/day)	3.9±0.1	4.7±0.1**	12.4±1.0‡	13.1±0.9‡
Food (g/day)	3.47±0.06	3.39±0.06	3.16±0.12	2.97±0.08
Other	(n = 22)	(n = 19)	(n = 11)	(n = 23)
Weight (g)	26.2±0.4	25.7±0.2	24.7±0.2†	23.1±0.3‡

Mean and standard error *p<0.05, **p<0.001 compared to control NSD (Independent samples Mann-Whitney U test or comparison of general linear model)

†p<0.05

‡p<0.001 compared to NSD (paired samples T-test).

Ext, Ext1^+/-Ext2^+/-, NSD, normal sodium diet; HSD, high sodium diet.