Figure 1.

TRERNA1 promotes the cell migration and invasion of HCC in vitro. A, Cell migration assays were performed using transwell assays in HepG2 and HepG2.215 cells. The average number of cells exhibiting migration from three random microscopic fields is presented in the histogram. B, Cell invasion assays were performed using Matrigel‐coated transwell membranes. The average number of cells exhibiting invasion from three random microscopic fields is presented in the histogram. C and D, Wound‐healing assays in TRERNA1‐overexpressing HepG2 cells and in TRERNA1‐depleted HepG2.215 cells. The scratch was measured at 0, 24 and 48 h. Data are presented as the mean ± SD; n = 3. *P < 0.05, **P < 0.01