TABLE 2.
Effects of 60 d of flaxseed lignan extract compared with placebo on urinary enterolignan excretion (n = 42)1
| Lignan | Placebo | Lignan extract | P value2 |
|---|---|---|---|
| SECO | 0.03 (0.006) | 2.95 (0.61) | <0.001 |
| END | 0.38 (1.01) | 5.19 (1.36) | <0.001 |
| ENL | 2.85 (0.67) | 13.62 (3.19) | <0.001 |
| ENL/SECO + END + ENL | 0.77 (0.03) | 0.62 (0.02) | <0.001 |
Urinary enterolignan excretion in µmol/24 h; values presented as back-transformed adjusted geometric means (geometric SDs) or back-transformed square root (SDs) for ratio ENL/SECO + END + ENL. END, enterodiol; ENL, enterolactone; SECO, secoisolariciresinol.
P values derived from linear mixed models evaluating the effects of flaxseed lignan extract compared with placebo on urinary lignan excretion adjusted for age, BMI, sex, intervention sequence, and assay batch.