. Author manuscript; available in PMC: 2020 Jul 31.

Published in final edited form as: J Infect Dis. 2019 Jul 31;220(5):820–829. doi: 10.1093/infdis/jiz201

Table 8.

Comparison of Influenza Mortality by Birth Cohort, 2000–2001 through 2016–2017 seasons - Relative Rate of Influenza Mortality During H3 Compared to H1 Predominant Seasons

	Prepandemic (2000–2001 to 2008–2009 Seasons)			Pandemic and Later (2009–2010 to 2016–2017 Seasons)

	Death Rate Per 100 000 (No. of Deaths)		H3 vs H1 Predominant Seasons	Death Rate Per 100 000 (No. of Deaths)		H3 vs HI Predominant Seasons

Cohort	HI Predominant Seasons	H3 Predominant Seasons	Relative Rate (95% Confidence Interval)	H1 Predominant Seasons	H3 Predominant Seasons	Relative Rate (95% Confidence Interval)

1918–1922	1.22 (220)	7.98 (1803)	6.54 (2.89–12.98)	7.29 (362)	41.12 (3173)	5.64 (1.08–18.74)
1933–1937	0.26 (96)	0.93 (433)	3.58 (1.99–6.46)	2.90 (645)	6.22 (2270)	2.14 (0.35–6.33)
1947–1951	0.10 (72)	0.25 (230)	2.50 (1.26–5.02)	1.52 (799)	1.37 (1203)	0.90 (0.30–1.94)
1957–1961	0.06 (53)	0.10 (109)	1.67 (0.75–4.26)	1.28 (860)	0.63 (704)	0.49 (0.20–0.95)
1968–1972	0.03 (21)	0.05 (55)	1.67 (1.05–4.19)	0.70 (437)	0.26 (276)	0.37 (0.17–0.66)
1977–1981	0.02 (19)	0.05 (45)	2.50 (0.58–3.94)	0.40 (246)	0.18 (185)	0.45 (0.25–0.75)
1985–1989	0.03 (26)	0.06 (63)	2.00 (0.99–4.47)	0.26 (169)	0.10 (113)	0.38 (0.27–0.74)

The bold indicates the value is statistically significant.