Table 1:

Comparison of reported lipid nanoprobe nanostructure platform with existing techniques for nEV isolation and enrichment.

Enrichment Technique		Mechanism		Speed/Rate		Volume	Efficiency		Purity		Cost	Point of Care
Ultracentrifugation5,32–34		Density		2–24 h		0.5–5 ml	2–25%		Medium/High		$ $ $	No
Immunocapture32,34		Antigen		1–5 h		500 μl	N/A		Medium/High		$ $	Somewhat
Precipitation33		Solubility		12–24 h		1–10 ml	N/A		Low		$	No
Lipid Nanoprobe6		Affinity		15 m		up to 1 ml	50–80%		Medium		$ $	Somewhat
LNP Nanostructure Platform		Affinity & Size		2 m-3 h 20 m		up to 2 ml	30%		High		$	Yes
	Poor				Acceptable					Good