Table 1.
Summary of demographics
| Parameter | Severe renal impairment (n = 8) | Moderate renal impairment (n = 8) | Healthy (n = 8) | Overall (n = 24) |
|---|---|---|---|---|
| Age (years) | 57 (11) | 63 (12) | 51 (7) | 57 (11) |
| Sexa | ||||
| Male | 6 (75.0) | 6 (75.0) | 6 (75.0) | 18 (75.0) |
| Female | 2 (25.0) | 2 (25.0) | 2 (25.0) | 6 (25.0) |
| BMI (kg/m2) | 30.6 (6.4) | 31.6 (4.9) | 29.3 (4.0) | 30.5 (5.1) |
| CrCl (mL/min) | 32.3 (17.7) | 56.0 (20.2) | 114.3 (26.1) | – |
| eGFR (mL/min/1.73 m2) | 21.1 (5.9) | 40.6 (8.2) | 89.3 (10.6) | – |
Data presented as mean (SD)
BMI body mass index, CrCl creatinine clearance, eGFR estimated glomerular filtration rate, SD standard deviation
an (%)