Table 3.
Outcomes of acute liver failure managed at the Victorian Liver Transplant Unit in a historical cohort† compared to the current series
| Aetiology |
TFS (%) |
OS (%) |
||||||||
|
1988-20011 |
2002-2017 |
P value |
1988-20011 |
2002-2017 |
P value | |||||
| n | % | n | % | n | % | n | % | |||
| Paracetamol | 20 | 69.0 | 62 | 73.8 | 0.614 | 21 | 72.4 | 65 | 77.4 | 0.589 |
| Non-paracetamol | 10 | 19.6 | 26 | 30.6 | 0.160 | 29 | 56.9 | 57 | 67.1 | 0.230 |
| Viral hepatitis | 2 | 18.2 | 10 | 38.4 | 0.228 | 5 | 45.5 | 18 | 69.2 | 0.173 |
| HBV | 2 | 25.0 | 7 | 35.0 | 0.609 | 4 | 50.0 | 14 | 70.0 | 0.318 |
| HAV | 0 | 0.0 | 3 | 75.0 | 0.047 | 1 | 0.33 | 3 | 75.0 | 0.270 |
| Drug/toxin induced | 3 | 60.0 | 5 | 29.4 | 0.211 | 4 | 80.0 | 12 | 70.6 | 0.678 |
| Autoimmune hepatitis | 0 | 0.0 | 3 | 33.3 | - | 0 | 0.0 | 6 | 66.7 | - |
| Indeterminate hepatitis | 5 | 18.5 | 2 | 9.5 | 0.381 | 15 | 55.5 | 14 | 66.7 | 0.435 |
| Other | 0 | 0.0 | 6 | 50.0 | 0.017 | 5 | 62.5 | 7 | 58.3 | 0.852 |
1
Gow et al[12], 2001. TFS: Transplant-free survival; OS: Overall hospital survival; HBV: Hepatitis B virus; HAV: Hepatitis A virus.