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. 2019 Jul 25;10:832. doi: 10.3389/fphar.2019.00832

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Copyright © 2019 Wang, Zhang, Huang, Wang, Ni, Lu, Hu, Deng, Zhu, Xie, Chen, Zhang, Qiu, Wen and Shang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The simulations of lamotrigine pharmacokinetic profiles in patients, (A) with different concomitant drugs and genetic types, at the same dose of 100 mg b.i.d.; (B) with the same target concentration range, at personalized dose regimens.