Table 3.
Allelic and genotype frequencies of the transporters MDR1, ABCG2, ABCC2, and SLC22A1 in Chinese patients with epilepsy. (n = 89).
| Gene | Genotype | Frequency (%) | Allele | Frequency (%) |
|---|---|---|---|---|
|
MDR1-C1236T (rs1128503) |
CC | 7 (7.9) | C | 66 (37.1) |
| CT | 52 (58.4) | T | 112 (62.9) | |
| TT | 30 (33.7) | |||
|
MDR1-G2677T (rs2032582) |
GG | 22 (24.7) | G | 89 (50.0) |
| AT | 8 (9.0) | A | 24 (13.5) | |
| AG | 12 (13.5) | T | 65 (36.5) | |
| GT | 33 (37.1) | |||
| AA | 2 (2.2) | |||
| TT | 12 (13.5) | |||
|
MDR1-C3435T (rs1045642) |
CC | 42 (47.2) | C | 118 (66.3) |
| CT | 34 (38.2) | T | 60 (33.7) | |
| TT | 13 (14.6) | |||
|
ABCG2 34G > A (rs2231137) |
GG | 32 (36.0) | G | 109 (61.2) |
| AG | 45 (50.6) | A | 69 (38.8) | |
| AA | 12 (13.5) | |||
|
ABCG2 421C > A (rs2231142) |
CC | 45 (50.6) | C | 129 (72.5) |
| CA | 39 (43.8) | A | 49 (27.5) | |
| AA | 5 (5.6) | |||
|
ABCC2-G1249A (rs2273697) |
GG | 72 (80.9) | G | 159 (89.3) |
| GA | 15 (16.9) | A | 19 (10.7) | |
| AA | 2 (2.2) | |||
|
SLC22A1 1222G > A (rs628031) |
GG | 41 (46.1) | G | 125 (70.2) |
| GA | 43 (48.3) | A | 53 (29.8) | |
| AA | 5 (5.6) | |||
|
SLC22A1 1022C > T (rs2282143) |
CC | 72 (80.9) | C | 159 (89.3) |
| CT | 15 (16.9) | T | 19 (10.7) | |
| TT | 2 (2.2) |