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. 2019 Jul 25;10:604. doi: 10.3389/fgene.2019.00604

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Copyright © 2019 Kudryavtsev, Serebriakova, Zhiduleva, Murtazalieva, Titov, Malashicheva, Shishkova, Semenova, Irtyuga, Isakov, Mitrofanova, Moiseeva and Golovkin

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Percentage of major Th, Tcyt, and Treg subsets (gating strategy based on CD45R0 and CD62L expression). Note. SAS (black circles, n = 38), severe aortic stenosis; MAS (black squares, n = 33), moderate aortic stenosis; HV (black triangles, n = 30), healthy volunteers. Naïve (CD45R0−CD62L+); CM, central memory (CD45R0+CD62L+); EM, effector memory (CD45R0+CD62L−); TEMRA, terminally differentiated CD45RA-positive effector memory (CD45R0−CD62L−); Treg, regulatory T cells. Differences between groups were evaluated by using nonparametric Mann–Whitney U-test.