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. 2019 Jul 25;10:460. doi: 10.3389/fendo.2019.00460

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Copyright © 2019 Balise, Cornelius-Green, Parmenter, Baxter, Kassotis, Rector, Thyfault, Paterlini, Palanza, Ruiz, Sargis and Nagel.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Body weight and basal glucose levels before and after high fat high sugar diet (HFHSD) at 11 months of age. Estimated marginal means (±SEM) of body weight before and after 3 days on HFHSD (A), and basal blood glucose levels before and after 3 days on HFHSD (B). For body weight n = 10, 8, 9, 10, 9, respectively, for vehicle, 1.5, 15, 150, and 1,500 μg/kg/day treatment groups. For basal glucose levels before HFHSD n = 9, 9, 8, 9, 8, and after HFHSD n = 10, 11, 9, 10, 10, respectively for vehicle, 1.5, 15, 150, and 1,500 μg/kg/day treatment groups. Two way ANOVA comparing within group before and after HFHSD ^*p < 0.05, and ^**p < 0.0125.