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. 2004 Apr 19;2004(2):CD004050. doi: 10.1002/14651858.CD004050.pub2

Kripke 1987.

Methods Allocation: 
 randomized, 'blocked randomization', crossover. 
 Blinding: double blind, 'rater blind'. 
 Duration: 5 days.
Participants Diagnosis: 
 Major depressive disorder (N = 4), bipolar disorder (N=1), endogenous depression (N = 6), schizo‐affective disorder (N = 2), minor depressive disorder (N = 1). RDC. 
 Inclusion criteria: 
 HDRS (24‐item) and BDI at least 15. 
 Exclusion criteria: psychotropic drugs. 
 N = 15 (14 completers). Age: mean 46 years. 
 Sex: F 1, M 14. 
 Setting: inpatients.
Interventions 1. Bright light (1500‐2500 lux for 6 patients 5‐6 AM for 1 hour, for 8 patients 5‐6 AM and 9‐10 PM for 2 hours). N = 7. 
 2. Dim red light (50 lux for 6 patients 5‐6 AM for 1 hour, for 8 patients 5‐6 AM and 9‐10 PM for 2 hours). N = 7. 
 Device: ceiling mounted lights.
Outcomes Mental state (HDRS, BDI, circadian self‐rating).
Notes Light only. Minor SD (1‐to‐2 hours before wakeup time). 
 No pharmacotherapy except for one patient.
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear