Mackert 1990.
| Methods | Allocation: randomized. Blindning: double blind, 'rater blind'. Duration: 7 days. | |
| Participants | Diagnosis: Major depressive disorder. RDC, ICD‐9. Exclusion criteria: seasonal depression, ophthalmological or oculomotor disorder, acute suicidality, IQ lower than 90. N = 42. Age: mean 54.2 years. Sex: F 34, M 8. Setting: inpatients. | |
| Interventions | 1. Bright white light (2500 lux 7‐9 AM for 2 hours). N = 22. 2. Dim red light (50 lux 7‐9 AM for 2 hours). N = 20. Device: light box. | |
| Outcomes | Mental state (HDRS, D‐S, D‐S', VAS, AMDP).
Adverse effects (C‐ L).
Patient expectation (subjective initial response).
Physiological monitoring (ECG, lab). Global improvement (CGI). |
|
| Notes | Light only. No pharmacotherapy. | |
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Allocation concealment? | Unclear risk | B ‐ Unclear |