| Methods |
Allocation: randomized.
Blindning: double blind, 'raters blind to light condition'.
Duration: 1 week, light therapy followed by one night of LPSD.
LPSD nonresponders. |
| Participants |
Diagnosis: Major depressive disorder (N = 5), bipolar disorder (N = 1). DSM‐IV.
Inclusion criteria: HDRS (17‐item) less than 40% reduction after LPSD.
Exclusion criteria: seasonal pattern, mood disorders due to general medical condition, retinal disorders.
N = 6.
Age: mean 48.7 years.
Sex: F 6, M 0.
History: duration of illness mean 11.7 years.
Setting: inpatients. |
| Interventions |
1. Bright white light (3000 lux 7‐9 AM and 5‐7 PM). N = 4.
2. Dim light (100 lux 7‐9 AM and 5‐7 PM). N = 2.
Device: light box. |
| Outcomes |
Mental state (HDRS ‐ 17‐item modified). Adverse effects. |
| Notes |
Light after LPSD of one night. Pharmacotherapy unchanged. |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment? |
Unclear risk |
B ‐ Unclear |
