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. 2004 Apr 19;2004(2):CD004050. doi: 10.1002/14651858.CD004050.pub2

van den Burg 1990.

Methods Allocation: randomized, crossover. 
 Blinding: not stated. 
 Duration: 2 days (two separate nights with simultaneous TSD and light intervention, separated by one recovery night).
Participants Diagnosis: Major depression (N = 21), atypical bipolar disorder (N = 1), atypical depression without seasonality (N = 1). DSM‐III. 
 Inclusion criteria: BDI more than 16 and interview. 
 N = 28 (23 completers). 
 Age: mean 47.2 years (completers). 
 Sex: F 11, M 12. 
 Setting: inpatients.
Interventions 1. Bright light (2000 lux from 11 PM to 7 AM for 8 hours) + TSD during two nights. N = 11. 
 2. Dim light (60 lux from 11 PM to 7 AM for 8 hours) + TSD during two nights. N = 12. 
 Device: light box (bright light intervention), dimly lit room (control).
Outcomes Mental state (BDI, AMS).
Notes Light adjunct to TSD. Pharmacotherapy unchanged. 
 Information on dropout groups insufficient. Results on completers only.
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear