Zirpoli 2002.
| Trial name or title | The sensitivity of melatonin to light suppression and light treatment in depressed and non‐depressed children. |
| Methods | |
| Participants | Diagnosis: Depression (DSM‐IV). Inclusion criteria: age 7‐18, no medication, no psychotic symptoms, no bipolar diagnosis, no recent history of substance abuse. |
| Interventions | 1. Morning light (7‐10 years: 2500 lux; 11‐18 years: 5000 lux). N = 11. 2. Evening light (age and light intensity as above). N = 10. 3. Dim red evening light (10 lux). N = 12. |
| Outcomes | SIGH‐SAD (both child and parent evaluation). CDI. Child Daily Mood Ratings. Expectation Questionnaire. Horne‐Ostberg Morningness‐Eveningness Questionnaire. Child psychiatrist evaluation. |
| Starting date | 1995. |
| Contact information | Dr. G. Zirpoli, Department of Psychiatry, University of California San Diego. E‐mail: gzirpoli@ucsd.edu. |
| Notes | Allocation: randomized.
Blindness: single‐blind.
Crossover study.
Duration: unknown. Supported in part by grants from the St.Giles Foundation, NARSAD, The Stanley Foundation, NIMH, NIH. |
Diagnostic tools: DSM‐IV = Diagnostic and Statistical Manual of Mental Disorders, fourth edition
Mental state scales: CDI = Child Depression Inventory HDRS = Hamilton Depression Rating Scale SIGH‐SAD = Structured Interview Guide for the Hamilton Depression Rating Scale‐SAD version