Fritzsche 2001a.
| Methods | Allocation: randomized, 'TSD respondents and nonrespondents randomized separately'. Blinding: double blind, 'rater blind'. Duration: light therapy 14 days (duration of study 16 days). Light starting the 3rd day after TSD. TSD respondents. | |
| Participants | Diagnosis: Major depressive disorder. Recurrent (N = 14, single episode N = 3, depressive episode of bipolar I (N = 3). DSM‐IV. Inclusion criteria: TSD responders. HDRS (21‐item) 16 or more. Exlusion criteria: mood disorder due to organic reasons or with opthalmological disorders. N = 20. Age: mean 46.5 years. Sex: F 13, M 7. Setting: inpatients. | |
| Interventions | 1. Bright white light (2500 lux in the morning for 2 hours). N = 11. 2. Dim red light (50 lux in the morning for 2 hours). N = 9. Device: light box. | |
| Outcomes | Mental state (HDRS). Unable to use ‐ Clinical improvement (50% reduction HDRS ‐ no data available). Mental state (Bf‐S ‐ no mean and SD available). |
|
| Notes | Light after TSD of one night. Pharmacotherapy unchanged. | |
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Allocation concealment? | Unclear risk | B ‐ Unclear |