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. 2004 Apr 19;2004(2):CD004050. doi: 10.1002/14651858.CD004050.pub2

Fritzsche 2001b.

Methods Allocation: randomized, 'TSD respondents and nonrespondents randomized separately'. 
 Blinding: double blind, 'rater blind'. 
 Duration: light therapy 14 days (duration of study 16 days). 
 Light starting on the 3rd day after TSD. 
 TSD nonrespondents.
Participants Diagnosis: Major depressive disorder. Recurrent (N = 11), single episode (N = 9). DSM‐IV. 
 Inclusion criteria: TSD nonresponders. HDRS (21‐item) 16 or more. Exclusion criteria: mood disorder due to organic reasons or with opthalmological disorders. 
 N = 20. 
 Age: mean 47.8 years. 
 Sex: F 13, M 7. 
 Setting: inpatients.
Interventions 1. Bright white light (2500 lux in the morning for 2 hours). N = 10. 
 2. Dim red light (50 lux in the morning for 2 hours). N = 10. 
 Device: light box.
Outcomes Mental state (HDRS).
Unable to use ‐ Clinical improvement (50% reduction HDRS ‐ no data available). 
 Mental state (Bf‐S ‐ no mean and SD available).
Notes Light after TSD of one night. Pharmacotherapy unchanged.
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear