Fritzsche 2001b.
| Methods | Allocation: randomized, 'TSD respondents and nonrespondents randomized separately'. Blinding: double blind, 'rater blind'. Duration: light therapy 14 days (duration of study 16 days). Light starting on the 3rd day after TSD. TSD nonrespondents. | |
| Participants | Diagnosis: Major depressive disorder. Recurrent (N = 11), single episode (N = 9). DSM‐IV. Inclusion criteria: TSD nonresponders. HDRS (21‐item) 16 or more. Exclusion criteria: mood disorder due to organic reasons or with opthalmological disorders. N = 20. Age: mean 47.8 years. Sex: F 13, M 7. Setting: inpatients. | |
| Interventions | 1. Bright white light (2500 lux in the morning for 2 hours). N = 10. 2. Dim red light (50 lux in the morning for 2 hours). N = 10. Device: light box. | |
| Outcomes | Mental state (HDRS). Unable to use ‐ Clinical improvement (50% reduction HDRS ‐ no data available). Mental state (Bf‐S ‐ no mean and SD available). |
|
| Notes | Light after TSD of one night. Pharmacotherapy unchanged. | |
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Allocation concealment? | Unclear risk | B ‐ Unclear |