Comparison 5. Olmesartan vs Placebo.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Change in trough SBP	2		Mean Difference (IV, Fixed, 95% CI)	Subtotals only
1.1 10 mg	1	53	Mean Difference (IV, Fixed, 95% CI)	‐7.0 [‐14.70, 0.70]
1.2 20 mg	2	303	Mean Difference (IV, Fixed, 95% CI)	‐9.91 [‐13.15, ‐6.68]
1.3 40 mg (Max Dose)	1	59	Mean Difference (IV, Fixed, 95% CI)	‐11.00 [‐20.55, ‐5.45]
2 Change in trough DBP	3		Mean Difference (IV, Fixed, 95% CI)	Subtotals only
2.1 5 mg	1	61	Mean Difference (IV, Fixed, 95% CI)	‐6.20 [‐11.24, ‐1.16]
2.2 10 mg	1	53	Mean Difference (IV, Fixed, 95% CI)	‐5.40 [‐10.07, ‐0.73]
2.3 20 mg	3	364	Mean Difference (IV, Fixed, 95% CI)	‐7.11 [‐8.94, ‐5.28]
2.4 40 mg (Max Dose)	1	59	Mean Difference (IV, Fixed, 95% CI)	‐6.8 [‐11.39, ‐2.21]
2.5 80 mg	1	64	Mean Difference (IV, Fixed, 95% CI)	‐9.5 [‐14.60, ‐4.40]