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. 2008 Oct 8;2008(4):CD003822. doi: 10.1002/14651858.CD003822.pub2

Comparison 7. Telmisartan vs Placebo.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Change in trough SBP 6   Mean Difference (IV, Fixed, 95% CI) Subtotals only
1.1 20 mg 3 374 Mean Difference (IV, Fixed, 95% CI) ‐4.83 [‐7.81, ‐1.86]
1.2 40 mg 6 658 Mean Difference (IV, Fixed, 95% CI) ‐8.34 [‐10.66, ‐6.01]
1.3 80 mg (Max Dose) 6 651 Mean Difference (IV, Fixed, 95% CI) ‐8.89 [‐11.21, ‐6.57]
1.4 120 mg 3 201 Mean Difference (IV, Fixed, 95% CI) ‐10.87 [‐15.34, ‐6.40]
1.5 160 mg 3 196 Mean Difference (IV, Fixed, 95% CI) ‐12.18 [‐16.65, ‐7.72]
2 Change in trough DBP 5   Mean Difference (IV, Fixed, 95% CI) Subtotals only
2.1 20 mg 2 97 Mean Difference (IV, Fixed, 95% CI) ‐6.16 [‐9.95, ‐2.38]
2.2 40 mg 5 379 Mean Difference (IV, Fixed, 95% CI) ‐6.26 [‐8.14, ‐4.38]
2.3 80 mg (Max Dose) 5 373 Mean Difference (IV, Fixed, 95% CI) ‐6.95 [‐8.86, ‐5.05]
2.4 120 mg 3 201 Mean Difference (IV, Fixed, 95% CI) ‐6.80 [‐9.52, ‐4.09]
2.5 160 mg 3 196 Mean Difference (IV, Fixed, 95% CI) ‐7.21 [‐9.87, ‐4.54]