1 Change in trough SBP |
6 |
|
Mean Difference (IV, Fixed, 95% CI) |
Subtotals only |
1.1 20 mg |
3 |
374 |
Mean Difference (IV, Fixed, 95% CI) |
‐4.83 [‐7.81, ‐1.86] |
1.2 40 mg |
6 |
658 |
Mean Difference (IV, Fixed, 95% CI) |
‐8.34 [‐10.66, ‐6.01] |
1.3 80 mg (Max Dose) |
6 |
651 |
Mean Difference (IV, Fixed, 95% CI) |
‐8.89 [‐11.21, ‐6.57] |
1.4 120 mg |
3 |
201 |
Mean Difference (IV, Fixed, 95% CI) |
‐10.87 [‐15.34, ‐6.40] |
1.5 160 mg |
3 |
196 |
Mean Difference (IV, Fixed, 95% CI) |
‐12.18 [‐16.65, ‐7.72] |
2 Change in trough DBP |
5 |
|
Mean Difference (IV, Fixed, 95% CI) |
Subtotals only |
2.1 20 mg |
2 |
97 |
Mean Difference (IV, Fixed, 95% CI) |
‐6.16 [‐9.95, ‐2.38] |
2.2 40 mg |
5 |
379 |
Mean Difference (IV, Fixed, 95% CI) |
‐6.26 [‐8.14, ‐4.38] |
2.3 80 mg (Max Dose) |
5 |
373 |
Mean Difference (IV, Fixed, 95% CI) |
‐6.95 [‐8.86, ‐5.05] |
2.4 120 mg |
3 |
201 |
Mean Difference (IV, Fixed, 95% CI) |
‐6.80 [‐9.52, ‐4.09] |
2.5 160 mg |
3 |
196 |
Mean Difference (IV, Fixed, 95% CI) |
‐7.21 [‐9.87, ‐4.54] |