Comparison 9. KT3‐671 vs Placebo.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Change in trough SBP	1		Mean Difference (IV, Fixed, 95% CI)	Subtotals only
1.1 40 mg	1	66	Mean Difference (IV, Fixed, 95% CI)	‐6.60 [‐14.21, 1.01]
1.2 80 mg	1	67	Mean Difference (IV, Fixed, 95% CI)	‐5.40 [‐12.77, 1.97]
1.3 160 mg	1	64	Mean Difference (IV, Fixed, 95% CI)	‐6.2 [‐13.68, 1.28]
2 Change in trough DBP	1		Mean Difference (IV, Fixed, 95% CI)	Subtotals only
2.1 40 mg	1	66	Mean Difference (IV, Fixed, 95% CI)	‐3.4 [‐7.22, 0.42]
2.2 80 mg	1	67	Mean Difference (IV, Fixed, 95% CI)	‐2.6 [‐6.31, 1.11]
2.3 160 mg	1	64	Mean Difference (IV, Fixed, 95% CI)	‐2.1 [‐6.07, 1.87]