6. Change in pulse pressure according to proportions of Max.
Proportion of recommended maximum dose (Max) | Number of studies | Weighted mean change from baseline in pulse pressure (95% CI) | |
ARBs | 1/8 Max | 5 | ‐1.1 (‐3.1, 0.9) |
1/4 Max | 18 | ‐2.1 (‐3.0, ‐1.1) | |
1/2 Max | 27 | ‐2.0 (‐2.6, ‐1.4) | |
Max | 13 | ‐2.5 (‐3.6, ‐1.5) | |
1.5 Max | 5 | ‐1.1 (‐2.2, 0.1) | |
2 Max | 3 | ‐2.9 (‐6.2, 0.4) | |
Max and above | 33 | ‐2.3 (‐2.9, ‐1.7) | |
Placebo | 34 | 1.1 (0.8, 1.5) |