Table 4.

Univariate association between ∆SJC and genotypic score for the expression of ‘CD39 on CD4 T cells’ at the ENTPD1 locus stratified by concomitant treatments

Patient group	Coefficient (SE)	P value	Sample size
All samples, adjusted for concomitant DMARD	−0.07 (0.02)	5e−05	2922
All samples, no adjustment for DMARD	−0.08 (0.02)	2e−05	2922
Samples not on concomitant DMARD	−0.02 (0.04)	0.5	691
Samples on concomitant DMARD	−0.09 (0.02)	1e−05	2231
Samples on concomitant MTX	−0.1 (0.03)	0.002	958

The coefficients are the effect sizes of the standardised score on the standardised phenotype. The phenotype is adjusted for covariates: baseline DAS components, gender, cohort, genotyping array, 10 genetic principal components.

DAS, Disease Activity Score; DMARD, disease-modifying antirheumatic drug; MTX, methotrexate; SJC, swollen joint count.