Table 2.
N-glycan neighborhood definitions
| Name | HexNAC |
Hex |
NeuAc |
Size | |||
|---|---|---|---|---|---|---|---|
| Min | Max | Min | Max | Min | Max | ||
| High mannose | 2 | 2 | 3 | 10 | 0 | 0 | 16 |
| Hybrid | 2 | 4 | 2 | 6 | 0 | 2 | 80 |
| Bi-antennary | 3 | 5 | 3 | 6 | 1 | 3 | 104 |
| Asialo-bi-antennary | 3 | 5 | 3 | 6 | 0 | 1 | 96 |
| Tri-antennary | 4 | 6 | 4 | 7 | 1 | 4 | 172 |
| Asialo-tri-antennary | 4 | 6 | 4 | 7 | 0 | 0 | 56 |
| Tetra-antennary | 5 | 7 | 5 | 8 | 1 | 5 | 240 |
| Asialo-tetra-antennary | 5 | 7 | 5 | 8 | 0 | 0 | 60 |
| Penta-antennary | 6 | 8 | 6 | 9 | 1 | 5 | 280 |
| Asialo-penta-antennary | 6 | 8 | 6 | 9 | 0 | 0 | 60 |
| Hexa-antennary | 7 | 9 | 7 | 10 | 1 | 6 | 300 |
| Asialo-hexa-antennary | 7 | 9 | 7 | 10 | 0 | 0 | 60 |
| Hepta-antennary | 8 | 10 | 8 | 11 | 1 | 7 | 150 |
| Asialo-hepta-antennary | 8 | 10 | 8 | 11 | 0 | 0 | 30 |
Note: These define the ranges of monosaccharides which will be used to classify a glycan composition as being a member of each neighborhood, and the number of combinatorial N-glycan compositions in each neighborhood.