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. 2019 Jun 30;11(2):79–84. doi: 10.15171/jcvtr.2019.15

Table 3. Individual drugs used in patients with chronic heart failure (n=200) .

Drug class Drug HFrEF (n=150) HFpEF (n=38) HFmrEF (n=12)
Diuretics Furosemide
Torsemide
Metolazone
Indapamide
Hydrochlorthiazide
88 (58.6%)
28 (18.6%)
2 (1.3%)
4 (2.6%)
1 (0.6%)
26 (68.4%)
8 (21%)
2 (5.2%)
-
1 (2.6%)
6 (50%)
4 (33.3%)
-
MRAs Spironolactone
Epleronone
64 (42.6%)
10 (5%)
22 (57.8%)
0
10 (83.3%)
ACEIs Enalapril
Ramipril
40 (26.6%)
30 (20%)
9 (23.6%)
5 (13.1%)
7 (58.3%)
5 (41.6%)
ARBs Losartan
Telmisertan
Olmesertan
4 (2.6%)
8 (5.3%)
3 (2%)
4(10.5%)
-
-
2 (16.6%)
BBs Metoprolol
Carvedilol
Bisoprolol
Nebivolol
52 (34.6%)
18 (12%)
4 (2.6%)
2 (1.3%)
-
-
-
-
Glycosides Digoxin 40 (26.6%) 2(5.2%) 6 (50%)
Antithrombotics Aspirin
Warfarin
62(41.3%)
26 (17.3%)
3 (7.8%)
-
5 (41.6%)
Inotropic agents Dobutamine 28 (14%) -
Dopamine 22 (11%) -
Noradrenaline 6 (3%) -
Nitrates GTN
Isosorbide dinitrate
8 (4%)
4 (2%)
-
-
Antiarrhythmics Amiodarone 10 (5%) -

Abbreviations: ACEIs, Angiotensin-converting enzyme inhibitors; ARBs, Angiotensin receptor blockers; BBs, Beta blockers; MRAs, Mineralocorticoid receptor antagonists; GTN, Glyceryl trinitrate; HFrEF, heart failure with reduced ejection fraction; HFpEF, heart failure with preserved ejection fraction; HFmrEF, heart failure with a mid-range ejection fraction.